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Ischemin sodium
CAS No.
Ischemin sodium ( —— )
Catalog No. M16925 CAS No.
A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameIschemin sodium
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NoteResearch use only, not for human use.
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Brief DescriptionA cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
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DescriptionA cell permeable CBP bromodomain inhibitor with Kd of 19 uM; inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity; protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight357.36
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Molecular FormulaC15H16N3O4SNa
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=CC(/N=N/C2=CC(C)=C(O)C=C2N)=C(C)C=C1C)([O-])=O.[Na+]
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Chemical Name5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.
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